{"id":129,"date":"2024-03-21T15:24:29","date_gmt":"2024-03-21T21:24:29","guid":{"rendered":"https:\/\/wildpharm-mx.com\/?page_id=129"},"modified":"2024-03-27T08:34:16","modified_gmt":"2024-03-27T14:34:16","slug":"butonil","status":"publish","type":"page","link":"https:\/\/wildpharm-mx.com\/index.php\/butonil\/","title":{"rendered":"Butonil"},"content":{"rendered":"

\"Butonil\"<\/h1>\n

BUTONIL 10 mg\/ml<\/h1>\n

(soluci\u00f3n est\u00e9ril para inyecci\u00f3n)<\/h1>\n

Reg. SAGARPA: Q-0609-008<\/h1>\n

Ver archivo en PDF<\/a><\/p>\n

 <\/p>\n

 <\/p>\n

PRESENTACI\u00d3N:<\/h2>\n

Frasco de 5 \u00f3 10 ml<\/p>\n

 <\/p>\n

COMPOSICI\u00d3N:<\/h2>\n

Cada ml contiene: Tartrato de butorfanol<\/p>\n

Veh\u00edculo c.b.p. – 1 ml<\/p>\n

 <\/p>\n

CLASIFICACI\u00d3N FARMACOL\u00d3GICA:<\/h2>\n

Analg\u00e9sico y sedante opioide sint\u00e9tico con acci\u00f3n agonista kappa y antagonista mu<\/p>\n

 <\/p>\n

ACCI\u00d3N FARMACOL\u00d3GICA:<\/h2>\n

Tiene afinidad por receptores mu actuando como antagonista competitivo, pero ejerce sus acciones analg\u00e9sicas y de sedaci\u00f3n actuando como agonista en receptores kappa.<\/p>\n

 <\/p>\n

INDICACIONES:<\/h2>\n

Para manejo del dolor, como sedante o pre-anest\u00e9sico en caballos (Equus ferus caballus).<\/p>\n

 <\/p>\n

CONTRAINDICACIONES:<\/h2>\n

No debe administrarse en equinos destinados para consumo humano. No debe utilizarse en equinos que hayan presentado hipersensibilidad previa al f\u00e1rmaco.<\/p>\n

 <\/p>\n

PRECAUCIONES:<\/h2>\n

Admin\u00edstrese con precauci\u00f3n (disminuya dosis a la mitad) en equinos d\u00e9biles o de edad avanzada, con problemas renales o hep\u00e1ticos o con traumatismo craneoencef\u00e1lico.<\/p>\n

 <\/p>\n

SEGURIDAD DURANTE PRE\u00d1EZ Y LACTACI\u00d3N:<\/h2>\n

No se recomienda su uso durante la pre\u00f1ez. Puede utilizarse durante la lactaci\u00f3n.<\/p>\n

 <\/p>\n

PERIODO DE RETIRO:<\/h2>\n

Butonil no debe ser utilizado en equinos para consumo humano por lo cual no se tiene un periodo de retiro.<\/p>\n

 <\/p>\n

VIA DE ADMINISTRACI\u00d3N:<\/h2>\n

Intramuscular o Intravenosa<\/p>\n

 <\/p>\n

DOSIS Y DIRECCIONES DE USO:<\/h2>\n

0.02 \u2013 0.2 mg\/kg dependiendo del efecto deseado seg\u00fan los siguientes protocolos. Ning\u00fan tratamiento debe exceder de 48 hrs debido a que puede observarse hipomotilidad marcada. 10 mg<\/p>\n

 <\/p>\n

1. Como analg\u00e9sico:<\/h3>\n

0.02 \u2013 0.1 mg\/kg IM dosis \u00fanica o bien c\/ 3- 4 hrs.
\n0.02 – 0.4 mg\/kg IV cada 3-4 hrs.
\n0.05mg\/kg c\/ 4 hrs I.M. post castraci\u00f3n x 24hrs<\/p>\n

Uso en combinaci\u00f3n con otros f\u00e1rmacos: Butorfanol 0.01 \u2013 0.04 mg\/kg I.V. en combinaci\u00f3n con:<\/p>\n

Acepromazina 0.04 mg\/kg I.V.
\nXilacina 0.1 \u2013 0.5 mg\/kg I.V.
\nDetomidina 0. 01 \u2013 0.02 mg\/kg<\/p>\n

En infusi\u00f3n para analgesia abdominal y post quir\u00fargica:<\/p>\n

Las infusiones proveen una analgesia o sedaci\u00f3n constante una vez que se haya administrado el bolo inicial.<\/p>\n

Bolo inicial de 0.02 mg\/kg seguida de la infusi\u00f3n de 0.013- 0.024 mg\/kg\/hr para 24 horas.<\/p>\n

Para dolor en casos de S\u00edndrome Abdominal Agudo (c\u00f3lico):<\/p>\n

0. 01 \u2013 0.05 mg\/kg I.V. s\u00f3lo o en combinaci\u00f3n con xilacina (0.02-0.1 mg\/kg I.M.)
\n0.06 \u2013 0.1 mg\/kg I.M. m\u00e1s detomidina 0.01 \u2013 0.02 mg \/kg<\/p>\n

Para el manejo del dolor en impactaci\u00f3n de colon mayor:<\/p>\n

0.04 \u2013 0.2 mg\/kg cada 3 \u2013 6hrs I.M.
\n0.02 \u2013 0.1 I .V. cada 3 \u2013 4 hrs<\/p>\n

Para el manejo de dolor en potros:<\/p>\n

0.05-0.2 mg\/kg I.V. o I.M. (puede ocasionar recumbencia en potros < 1 mes)
\nA dosis bajas, puede ser combinado con diazepam 0.025-0.05 mg\/kg I.V.<\/p>\n

 <\/p>\n

2.- Como pre-anest\u00e9sico para cirug\u00eda ambulatoria o inmovilizaci\u00f3n qu\u00edmica:<\/h3>\n

Sedaci\u00f3n del caballo para procedimientos de pie en combinaci\u00f3n con alfa adren\u00e9rgicos:<\/p>\n

0.02 \u2013 0.05 mg\/kg I.V.; 0.05 \u2013 0.1 mg\/kg I.M.
\n0.01 \u2013 0.04 mg\/kg I.V. combinado con xilacina 0.1 – 0.5 mg\/kg I.V.
\n0.05mg\/kg m\u00e1s 0.1 mg\/kg detomidina<\/p>\n

Para pre-anestesia:<\/p>\n

Sedar primeramente con xilacina (0.5 -1 mg\/kg I.V. \u00f3 2 mg\/kg I.M.), o bien, tambi\u00e9n puede ser usada detomidina (0.02 mg\/kg I.V.). Despu\u00e9s de 5 \u2013 10 minutos administrar el butorfanol 0.01-0.04 mg\/kg I.V., (antes del anest\u00e9sico a utilizar ej. Ketamina, Propofol, etc).<\/p>\n

<\/h2>\n

SOBREDOSIS:<\/h2>\n

A dosis intravenosas de 10 veces las recomendadas (1 \u2013 2 mg\/kg), cada 4hrs durante 2 d\u00edas, se han presentado nistagmos, salivaci\u00f3n, convulsiones, hipertermia, taquipnea y disminuci\u00f3n de motilidad intestinal hasta constipaci\u00f3n. Efectos sobre el SNC, como hiperexcitabilidad, con inquietud en conjunto de ataxia leve. Estos signos se consideraron transitorios una vez suspendida la administraci\u00f3n del medicamento<\/p>\n

<\/h2>\n

TRATAMIENTO<\/h2>\n

Los signos de sobredosis pueden ser tratados con naltrexona a 1.34 \u00b1 0.42 mg\/kg o en relaci\u00f3n a la cantidad de mg totales administrados de butorfanol a raz\u00f3n de 2 a 3 mg por cada mg de butorfanol utilizado. Adicionalmente se puede mantener al paciente con suplementaci\u00f3n de O2, agentes vasopresores, fluidos y ventilaci\u00f3n asistida en caso de ser necesario.<\/p>\n

 <\/p>\n

EFECTOS SECUNDARIOS:<\/h2>\n

Puede presentarse ataxia transitoria y sedaci\u00f3n, aunque tambi\u00e9n se han reportado excitaci\u00f3n, disforia o euforia. En uso continuo mayor a 48 horas puede llegar a ocurrir \u00edleo paral\u00edtico por disminuci\u00f3n de motilidad intestinal.<\/p>\n

 <\/p>\n

ADVERTENCIAS DE USO<\/h2>\n

Debe adrenocortical, as\u00ed como en pacientes geriatras o gravemente debilitados. Se debe utilizar con suma precauci\u00f3n en pacientes con traumatismo craneoencef\u00e1lico, presi\u00f3n intracraneana elevada o alguna otra disfunci\u00f3n del SNC (v. gr. coma) debido a la probable asociaci\u00f3n con un incremento en la retenci\u00f3n del CO2 y la consecuente elevaci\u00f3n de la presi\u00f3n del l\u00edquido cerebro espinal.<\/p>\n

Debe ser utilizado con precauci\u00f3n en pacientes con hiporitoidismo, insuficiencia.<\/p>\n

 <\/p>\n

INSTRUCCIONES DE ALMACENAJE:<\/h2>\n

Debe mantenerse protegido de la luz, en un lugar fresco y seco a no m\u00e1s de 65% de humedad relativa y a una temperatura ambiente entre 15\u00b0C y 30\u00b0C.<\/p>\n

 <\/p>\n

\u00abM\u00c1NTENGASE FUERA DEL ALCANCE DE LOS NI\u00d1OS Y ANIMALES DOM\u00c9STICOS\u00bb<\/h3>\n

\u00abSU VENTA REQUIERE RECETA M\u00c9DICA CUANTIFICADA\u00bb<\/h3>\n

\u00abPARA USO EXCLUSIVO DEL M\u00c9DICO VETERINARIO\u00bb<\/h3>\n","protected":false},"excerpt":{"rendered":"

BUTONIL 10 mg\/ml (soluci\u00f3n est\u00e9ril para inyecci\u00f3n) Reg. SAGARPA: Q-0609-008 Ver archivo en PDF     PRESENTACI\u00d3N: Frasco de 5 \u00f3 10 ml   COMPOSICI\u00d3N: Cada ml contiene: Tartrato de butorfanol Veh\u00edculo c.b.p. – 1 ml   CLASIFICACI\u00d3N FARMACOL\u00d3GICA: Analg\u00e9sico y sedante opioide sint\u00e9tico con acci\u00f3n agonista kappa y antagonista mu   ACCI\u00d3N FARMACOL\u00d3GICA: Tiene […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-129","page","type-page","status-publish","hentry"],"yoast_head":"\nButonil - Wildlife Pharmaceuticals Mexico<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wildpharm-mx.com\/index.php\/butonil\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Butonil - Wildlife Pharmaceuticals Mexico\" \/>\n<meta property=\"og:description\" content=\"BUTONIL 10 mg\/ml (soluci\u00f3n est\u00e9ril para inyecci\u00f3n) Reg. 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